Combining an SSRI and pregnancy is a potentially dangerous combination.
There is some controversy regarding taking antidepressants during pregnancy due to the potential harm to developing fetuses.
For example, drugs such as Paxil are associated with increased risk of miscarriage. In addition, they found that a combination of different antidepressants doubled the risk of miscarriages.
In addition, Celexa, Paxil, Prozac, and Zoloft have been associated with PPHN (persistent pulmonary hypertension of the newborn) when these drugs were taken during the last half of pregnancy.
PPHN is a rare but serious and potentially life-threatening condition that affects newborns. In addition to possible PPHN, babies exposed to SSRI during pregnancy also experience an increased risk of developing other birth defects and health problems such as Omphalocele, septal heart defects, Anencephaly, and Craniosynostosis.
If you are pregnant or thinking about starting a family and taking a selective serotonin reuptake inhibitor, inform your doctor right away in order to discuss your options and amend your treatment plan.
For example, often mild depression can be managed with additional therapy or other holistic or non-medication treatment approaches.
If your depression is severe, however, or if you have a recent history of depression, or have a history of major depressive episodes the decision becomes more complicated.
The risk of depressive relapse in the mother may be greater than the potential risks of the developing baby when taking selective serotonin reuptake inhibitors.
Such factors must be weighed by you and your doctor on a cost-benefit analysis scale in order to determine the best course of action for both mother and baby.
As a result of the health complications listed above, the pros and cons of taking an SSRI during pregnancy must be weighed carefully on an individual basis.
It is vital to work with your doctor to determine the least risky course of action.
On a case by base basis, doctors and patients can work together via a cost-benefit paradigm with respect to managing the a mother's depression and the baby's health.
If you and your doctor do alter or reduce your dose of your antidepressant medication while pregnant, be sure to report any increase in depression symptoms to your doctor during this process.