Paxil Birth Defects

Does Paxil Cause Birth Defects? Find Out Here...


Research suggests an increased risk of Paxil birth defects for pregnant women who take Paxil during pregnancy.

(Also read this important warning about Paxil and pregnancy).

According to two different studies, women who took Paxil during pregnancy were one and a half to two times more likely to have a baby with heart defects compared to women taking other antidepressants and women in the general population.

Other studies have shown a link between taking Paxil during pregnancy and a serious condition called PPHN (persistent pulmonary hypertension of the newborn), abdominal malformations, cranial malformations, and other health complications.

This article will examine each of these potential birth defects in greater detail. So let's get started...

Heart Defects

In December 2005, the FDA issued a warning regarding the increased risks of birth defects when taken during the first trimester of pregnancy. Specifically, the studies showed the heart defects were mostly atrial and ventricular septal defects which are characterized by holes in the walls of the heart chambers. If severe enough, they may require surgery.

PPHN

The New England Journal of Medicine published a study linking Paxil and PPHN (persistent pulmonary hypertension of the newborn). The study concluded that women who used Paxil after week 20 of pregnancy were six times more likely to give birth to a baby with PPHN.

PPHN is a serious and potentially life-threatening condition. In addition, babies with PPHN frequently suffer brain damage, hearing damage, speech deficits, developmental delays, and other neurological and cognitive deficits.

Other Complications

paxil birth defects

Other possible Paxil reactions can include difficulties with respiration, seizures, vomiting, low blood sugar, tremors, and agitation.

Conclusion About Paxil Birth Defects

For pregnant women, the US Food and Drug Administration has mandated a level D warning which means that studies done in pregnant women have shown risks to the fetus. The risks could be large or small; ongoing research is being conducted. 

Different countries have passed laws pertaining to Paxil and similar antidepressants. In England, for instance, it is not recommended for pregnant women to take SSRI antidepressants.

Safety Precautions

As a result of potential health risks to both mother and developing baby, if you become pregnant or are thinking about becoming pregnant while taking Paxil consult with your doctor in order to discuss your options. Often your doctor can arrange a treatment plan that both treats your depression symptoms without causing potential harm to your baby.

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